Online-Inquiry > 항암유효성평가지원센터

Therapeutics

Cytotoxic drugs Immuno-oncology Targeted agents Oncolytic virus Others

합성물질 천연물 단백질 유전자 세포 Others

Others

Biomarker Diagnostic panel

Brain Breast Cervix Cholangiocarcinoma Colon Esophagus Fibrosarcoma Head & neck Kidney Leukemia Liver Lung Melanoma Ovary Pancreas Prostate Stomach Others :

Target discovery Hit Lead Candidate Clinical trial

in vitro efficacy evaluation

in vivo efficacy evaluation

Toxicology PK/PD Others

in vitro efficacy evaluation

Cell viability / Death assay / IC₅₀ calculation / Synergy index in vitro tumorigenic potential Resistance Enzyme assay Signal pathway assay Histological analysis Organelle staining Biomarker assay MOA & POC verification Target enzyme-based screen Phenotype-based screen High throughput screen Organoid

in vivo efficacy evaluation

Tumor growth inhibition Metastasis inhibition Immune cell infiltration Resistance Radiotherapy response Histological analysis MOA & POC verification Biomarker assay

Xenograft

세포주 환자유래

Subcutaneous xenograft Orthotopic xenograft Metastasis xenograft Patient-derived xenograft

Syngeneic

Subcutaneous syngeneic Orthotopic syngeneic Metastasis syngeneic Spontaneous syngeneic (GEM)

in vivo imaging

MRI PET/PET-MR CT Optical Others

예비안전성평가

Target organ toxicity Cardiovascular toxicity Combined exploratory toxicity Tissue Cross Reactivity Others

DMPK

in vitro ADME assay Cardiovascular toxicity Combined exploratory txicity Tissue Cross Reactivity Others

자문

MRI PET/PET-MR CT Optical