List of Models
CANCER TYPE |
Human |
Mouse |
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Bladder |
J82, T24, UM-UC-3 |
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Brain |
SF268, SF295, SF539, SNB19, SNB5, U-251 |
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Breast |
BT-549, Hs 578T, MCF7, MCF10A, MDA-MB-231, MDA-MB-468, SK-BR-3, T47D |
4T1, 4T1-Luc-TdTomato |
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Cervix |
A431, CaSki, C33, HeLa, SiHa |
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Cholangiocarcinoma |
SNU-1079, SNU-1196, SSP-25, TFK-1 |
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Colon |
Caco-2, COLO205, DLD-1, HCT-8, HCT-15, HCT-116, HT-29, KM12C, LoVo, LS1034, NCI-H716, NCI-H747, SNU-769B, SNU-1047, SNU-1235, SNU-C1, SNU-C2A, SNU-C2B, SNU-C5, SW403, SW480, SW620, RKO, WiDr |
CT26, CT26-Luc, MC38, MC38-Luc |
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Esophagus |
OE33 |
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Fibrosarcoma |
FSa-ll |
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Glioblastoma |
GL26 |
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Head and Neck |
CAL27, SCC-9, SCC-15, SCC-25 |
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Kidney |
ACHN, A-498 Caki-1, RXF393, SN12C, SN12C-PM6, TK10, UO31, 786-O |
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Liver |
Hep3B, HepG2, HepG2-Luc-Fluc, Huh7, SK-HEP-1, SNU-182, SNU-398, SNU-449 |
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Lung |
A549, A549-Luc, Calu-1, Calu-3, EKVX, HCC15, HCC78, HCC95, HCC366, HCC827, HOP62, HOP92, LC-2/ad, LK-2, NCI-H23, NCI-H69, NCI-H82, NCI-H146, NCI-H187, NCI-H209, NCI-H226, NCI-H322M, NCI-H358, NCI-H441, NCI-H460, NCI-H520, NCI-H522, NCI-H526, NCI-H596, NCI-H647, NCI-H820, NCI-H1299, NCI-H1385, NCI-H1395, NCI-H1473, NCI-H1573, NCI-H1581, NCI-H1650, NCI-H1666, NCI-H1703, NCI-H1781, NCI-H1944, NCI-H1975, NCI-H2009, NCI-H2170, NCI-H2228, NCI-H2286, NCI-H3122, PC9 |
LLC1 LLC1-Luc |
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Melanoma |
A375-P, LOX-IMVI, Malme-3M, M14, MDA-MB-435, SK-MEL-2, SKMEL-5, SKMEL-28, UACC-62, UACC-257 |
B16-F10 |
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Ovary |
A2780, ES-2-Luc, IGROV1, NCI/ADR-RES, OVCAR-3, OVCAR-3-Luc, OVCAR-4, OVCAR-5, OVCAR-8, SK-OV-3, SK-OV-3-Luc, SNU-8, SNU-251, UWB1.289 + BRCA1 null, UWB1.289 + BRCA1 overexpression |
ID8 |
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Pancreas |
AsPC-1, AsPC-1-Luc, BxPC-3, BxPC-3-Luc, MIAPaCa-2, PANC-1 |
PAN 02 |
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Prostate |
DU 145, LNCaP, PC3, VCaP, 22Rv1 |
TRAMP-C1 |
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Stomach |
OE19, SNU-1, SNU-5, NCI-N87 |
Service
- In vitro drug efficacy test : Cell viability / Death assay / IC50 calculation / Synergism analysis
- In vitro tumorigenic potential test : Clonogenic assay
- Signal pathway analysis : Immuno blotting, Immunoprecipitation, ELISA, Q-PCR, Chromatin Immunoprecipitation, Transfection, Protein binding assay
- Enzyme assay : Kinase assay, Methyltransferase assay
- Immunocytochemistry, TUNEL staining, Immunofluorescence staining, Hypoxia staining, Pimonidazole, ROS staining, Calcium/zinc ion staining, MitoTracker/sensor staining, LysoTracker/sensor staining, Autophagic vacuole staining
- MOA 검증
Service example (IC50 calculation)
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Identifying the combined effect by calculating
the combination index(CI) in cell lines -
Enzyme assay & IC50 calculation
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In vitro cell viability & IC50 calculation